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There is still much debate in the scientific community regarding how bovine spongiform encephalopathy (BSE) is spread. At the present time, BSE is thought to be spread in tissue from the central nervous system (brain, spinal cord) as well as the distal ileum (portion of the small intestine), some of which can be present in meat and bone meal. BSE is not spread by animal-to-animal contact. In other words, an animal infected with BSE cannot infect another animal with which it is penned or pastured. Little is known regarding the minimum amount of prion material that can cause an infection.
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