The reapplication schedule is site-specific. One strategy is to apply baits twice yearly. The first application should be made after the late spring mating flights have occurred. Suppression should last until fall, when the next application should be made. The fall application will help suppress ants until the following spring. This schedule can be followed every year if there is reinfestation from outlying fire ant colonies. Another strategy is to wait until fire ant mounds exceed 20 per acre, then reapply the bait. In situations where early spring control is most desirable, a single bait application in late summer or fall makes sense.

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