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Disease: Hyperkalemic Periodic Paralysis (HYPP)

Last Updated: September 20, 2011

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Hyperkalemic periodic paralysis is an inherited disease of Quarter Horses. At least one of the parents of an affected animal must also carry the gene and/or be affected, but not necessarily both because this is a dominant condition and only one abnormal gene need be present.

HYPP is characterized by:

  • Intermittent attacks of muscle weakness which can appear as muscle tremors
  • Weakness
  • Disorientation
  • Convulsions

Attacks frequently occur suddenly, like a seizure, choking, or colic-like symptoms and may resolve just as quickly.

Diagnosis of HYPP can be made from a blood sample by the identification of the gene using molecular techniques. Because the disease is genetic, there is no cure; however, management of the diet and in some cases medication may prevent clinical manifestation of the disease in a positively tested horse.

 

 

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