Affected animals will be reluctant or unable to drink, eat or walk, and they will lose weight rapidly. Blisters (vesicles) may form in the animal's mouth or muzzle, causing slobbering and drooling. Later, the blisters will break, forming raw patches or ulcers. Blisters and sores also can develop on the animal's teats, causing mastitis in dairy cattle. Blisters on the feet result in lameness. Swine and cattle usually will show signs of disease within two to seven days after being exposed to the virus. Sheep and goats may have only minimal clinical signs of disease after an incubation period of up to 14 days.
